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Hollfelder Group

Ph.D

Joined the Hollfelder group: October 2021

Background and Current Projects:  I graduated from AgroParisTech, an institute of Technology for Life, Food and Environment sciences, where I specialised in biotechnology and molecular and cell bioengineering. My previous work focused on the dynamics of epigenetic marks during the exit from pluripotency in mouse embryonic stem cells. After realizing that our knowledge of mammalian embryology was predominantly based on mouse studies, I decided to focus on human and non-human primate development. During my PhD, I aim to develop stem cell models for early primate embryogenesis by taking advantage of a cross-disciplinary approach using microfluidics and stem cell biology. The development of cellular models for early primate development could provide a powerful functional platform to delineate the signalling pathways and transcription factor networks involved in human development.;

Interests: I enjoy hiking and discovering new food places!

 

Publications

[3] Munger, C.; Kohler, T. N.; Slatery, E.; Ellermann, A. L.; Bergmann, S.; Penfold, C.; Ampartzidis, I.; Chen, Y.; Hollfelder, F.;  Boroviak, T. E.  Microgel culture and spatial identity mapping elucidate the signalling requirements for primate epiblast and amnion formation. Development 2022, 149, 20. Link

[2] Schindler M, Siriwardena D, Kohler TN, Ellermann AL, Slatery E, Munger C, Hollfelder F, Boroviak TE. Agarose microgel culture delineates lumenogenesis in naive and primed human pluripotent stem cells. Stem Cell Reports 16, 5 (2021). Link.

[1] Bergmann, S., Schindler, M., Munger, C. et al. Building a stem cell-based primate uterus. Commun Biol 4, 749 (2021). Link

Contact Details

Department for Physiology
Development and Neuroscience Physiology Building
G-Floor Downing Street
Cambridge CB2 3EG
Email: cm2040@cam.ac.uk